Glycogen Synthesis The modification of compounds to energy storage materials is a key component to life on Earth. Most prokaryotes and eukaryotes use glucose as the basic building block for starch and glycogen synthesis. Each of these multi-step reactions require the use of enzymes, one of which is the branching enzyme. This branching enzyme modifies the a-1,4 glycosyl linkages to a-1,6 glycosyl linkages at the ends of the growing glucan chain. This is important as it speeds up both the synthesis and degradation processes. The a-linkage network increases the area for both synthesis and degradation as both occur at the ends of the molecule. The more ends there are on the glucan chain, the more glycosyl linkages can be formed or broken. Dehydolization occurs in the synthesis reaction, when a water molecule is produced during the formation of an a-1,4 bond. The resulting linkage network allows the molecule to be more soluble than the straight linear chain. The increase in solubility increases the storage capacity.